Platelet Rich Plasma

Your body wants to heal, it just needs some help making that happen. In many cases after an
injury, the natural healing process takes its course and an area is still injured. This then turns
into a degenerative condition with the associated changes in the tissue texture that appears as
scar tissue and an associated inflammatory chemical milieu of growth factors that can impair

I often explain healing everything from a wrinkle to a rotator cuff as healing a chronic wound. We
just need to create the right conditions for healing which involves new blood vessels, oxygen,
nutrition, the appropriate level of anabolic hormones and growth factors.

Platelet Rich Plasma is a product derived from your own blood. We draw anywhere from 60-240
cc of blood and process it in a sterile processing container that is spun in a centrifuge in order to
separate the different layers of the blood out. The Red Blood cells go the bottom, the platelets
containing growth factors reside in the middle layer known as the Buffy Coat, and the Plasma is
on the top.

The effectiveness of PRP is largely dependent on the quantity of platelets obtained in this
process. The type of centrifuge and kit that we use at SFIIRM is able to concentrate platelets by
5-7 times their baseline which is enough to stimulate the production of new blood vessels and
connective tissue in the area treated.

The other variables that can change the effectiveness of PRP are the levels of white and red
blood cells found in the PRP. In general, Red Blood cells are inflammatory and do not contribute
any regenerative effects. These are minimized in our processing of the PRP by utilizing a two
spin technique, that first removes the Red Blood Cells and then concentrates the platelets. In
the end we are left with a Pure Prp that is ideal for both musculoskeletal and aesthetic

One other immunomodulatory substance known as Ozone gas, is added to most PRP
treatments in order to further refine the chemical milieu. O3 is a free radical that is able to
reduce levels of inflammatory growth factors found in degenerative conditions and increase
anabolic growth factors that aid in the healing process. Aside from that, Ozone quickly becomes
Oxygen in the tissue, which dissolves into the tissue leaving an oxygen rich environment for

The most important variable in determining the effectiveness of PRP is the correct placement of
the product. Using a high definition ultrasound, we are able to accurately place the PRP into the
desired location. Determining the desired location involves a clinical exam and diagnostic
ultrasound prior to the treatment. This is where the skill of the practitioner can make the
difference between an effective treatment and one that may be ineffective or not address the
underlying cause and be likely to recur. As an Osteopath and Prolotherapist, Dr. Wardwell looks
at the musculoskeletal system with an extra layer of attention to the effect of soft tissue strain
patterns, hidden tendon weaknesses mediating distant bio-mechanical problems, and
ligamentous laxity predisposing to tendon and joint pathology. Proper bio-mechanical alignment
is assessed in order to address the abnormal forces that caused the pathology in the first place.

Lastly, Platelet Rich Plasma is utilizing your bodies innate healing capacity in order to achieve
the desired effect. Utilizing PRP in the context of functional medicine allows us to optimize your
molecular machinery so that you are primed for healing when we put the PRP in all the right


450 Sutter St, Ste 1341 San Francisco, Ca 94109
ph: 415-606-0309